Article

Mature microRNA-binding protein QKI promotes microRNA-mediated gene silencing

2023-03-15

Abstract excerpt

<h4>ABSTRACT</h4> Although Argonaute (AGO) proteins have been the focus of microRNA (miRNA) studies, we observed AGO-free mature miRNAs directly interacting with RNA-binding proteins, implying the sophisticated nature of fine-tuning gene regulation by miRNAs. To investigate microRNA-binding proteins (miRBPs) globally, we analyzed PAR-CLIP data sets to identify RBP quaking (QKI) as a novel miRBP for let-7b. Potent...

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Literature Corpus work: b798002c-bf3e-54bc-8f9b-fc9369435b15
DOI: 10.1101/2023.03.15.532749

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