Article
MtiBase: a database for decoding microRNA target sites located within CDS and 5'UTR regions from CLIP-Seq and expression profile datasets.
Database : the journal of biological databases and curation - 1 Jan 2015
Guo Zhi-Wei, Xie Chen, Yang Jian-Rong, Li Jun-Hao, Yang Jian-Hua, Zheng Limin
Abstract excerpt
MicroRNAs (miRNAs) play an important role in the regulation of gene expression. Previous studies on miRNA functions mainly focused on their target sites in the 3' untranslated regions (UTRs) of mRNAs. However, increasing evidence has revealed that miRNAs can also induce mRNA degradation and mediate translational repression via complementary interactions with the coding sequence (CDS) and 5'UTR of mRNAs. In this...
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