Article

The rise and fall of an emerging SARS-CoV-2 variant with the spike protein mutation L452R

2021-07-07

Abstract excerpt

Emerging SARS-CoV-2 variants may threaten global vaccination efforts and awaited reduction in outbreak burden. In this study, we report a novel variant carrying the L452R mutation that emerged from a local B.1.362 lineage, B.1.362+L452R. The L452R mutation is associated with the Delta and Epsilon variants and was shown to cause increased infection and reduction in neutralization in pseudoviruses. Indeed, the B.1.3...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b78693b7-ae49-5529-9bac-4720e7ae7204
DOI: 10.1101/2021.07.03.21259957

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The rise and fall of an emerging SARS-CoV-2 variant with the spike protein mutation L452RDOI 10.1101/2021.07.03.21259957Read

Local emergence and decline of a SARS-CoV-2 variant with mutations L452R and N501Y in the spike proteinSemantic proximity Read

A novel B.1.1.523 SARS-CoV-2 variant that combines many spike mutations linked to immune evasion with current variants of concernSemantic proximity Read

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein.Semantic proximity Read

SARS-CoV-2 spike E156G/Δ157-158 mutations contribute to increased infectivity and immune escape.Semantic proximity Read

A SARS-CoV-2 Variant with L452R and E484Q Neutralization Resistance MutationsSemantic proximity Read

Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variantsSemantic proximity Read

Novel SARS-CoV-2 variants: the pandemics within the pandemic.Semantic proximity Read

Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants.Semantic proximity Read

Epidemiology and Characteristics of SARS-CoV-2 Variants of Concern: The Impacts of the Spike MutationsSemantic proximity Read

Rapidly emerging SARS-CoV-2 B.1.1.7 sub-lineage in the United States of America with spike protein D178H and membrane protein V70L mutations.Semantic proximity Read

Functional and structural characterization of the SARS-CoV-2 spike N481K mutation.Semantic proximity Read

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.Semantic proximity Read