Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.

doi:10.1016/j.cell.2021.04.025

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Article

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.

Cell - 24 Jun 2021

Deng Xianding, Garcia-Knight Miguel A, Khalid Mir M, Servellita Venice, Wang Candace, Morris Mary Kate, Sotomayor-González Alicia, Glasner Dustin R, Reyes Kevin R, Gliwa Amelia S, Reddy Nikitha P, Sanchez San Martin Claudia, Federman Scot, Cheng Jing, Balcerek Joanna, Taylor Jordan, Streithorst Jessica A, Miller Steve, Sreekumar Bharath, Chen Pei-Yi, Schulze-Gahmen Ursula, Taha Taha Y, Hayashi Jennifer M, Simoneau Camille R, Kumar G Renuka, McMahon Sarah, Lidsky Peter V, Xiao Yinghong, Hemarajata Peera, Green Nicole M, Espinosa Alex, Kath Chantha, Haw Monica, Bell John, Hacker Jill K, Hanson Carl, Wadford Debra A, Anaya Carlos, Ferguson Donna, Frankino Phillip A, Shivram Haridha, Lareau Liana F, Wyman Stacia K, Ott Melanie, Andino Raul, Chiu Charles Y

Abstract excerpt

We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples from 44 counties in California, a state in the western United States. Named B.1.427/B.1.429 to denote its two lineages, the variant emerged in May 2020 and increased from 0% to >50% of sequenced cases from September 2020 to January 2021, showing...

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PMID: 33991487
DOI: 10.1016/j.cell.2021.04.025
PMCID: PMC8057738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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