Article

Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings

2024-07-24

Abstract excerpt

Cellular electrophysiology is the foundation of many fields, from basic science in neurology, cardiology, oncology to safety critical applications for drug safety testing, clinical phenotyping, etc. Patch-clamp voltage clamp is the gold standard technique for studying cellular electrophysiology. Yet, the quality of these experiments is not always transparent, which may lead to erroneous conclusions for studies and...

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Literature Corpus work: b777819a-315d-5e71-b82b-22f4a8e37f5e
DOI: 10.1101/2024.07.23.604780

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