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Article

Large-scale synthetic data enable digital twins of human excitable cells

2025-09-07

Abstract excerpt

<h4>ABSTRACT</h4> Individual variability shapes how diseases manifest, how patients respond to therapy, and how rare phenotypes arise. Conventional experimental approaches obscure variation by averaging, which limits mechanistic insight and predictive accuracy. We present a computational framework that builds digital twins of human-induced pluripotent stem cell-derived cardiomyocytes from a single optimized volta...

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Identifiers and source

Literature Corpus work
e4076a4a-6da5-50c3-ae56-ebfd8c01f5dc
DOI
10.1101/2025.09.03.674034
Open publication

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Large-scale synthetic data enable digital twins of human excitable cellsDOI 10.1101/2025.09.03.674034
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