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Article

From ionic to cellular variability in human atrial myocytes: an integrative computational and experimental study.

American journal of physiology. Heart and circulatory physiology - 1 May 2018

Muszkiewicz Anna, Liu Xing, Bueno-Orovio Alfonso, Lawson Brodie A J, Burrage Kevin, Casadei Barbara, Rodriguez Blanca

Abstract excerpt

Variability refers to differences in physiological function between individuals, which may translate into different disease susceptibility and treatment efficacy. Experiments in human cardiomyocytes face wide variability and restricted tissue access; under these conditions, computational models are a useful complementary tool. We conducted a computational and experimental investigation in cardiomyocytes isolated...

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Identifiers

PMID: 29351467
DOI: 10.1152/ajpheart.00477.2017
PMCID: PMC6008144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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