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DiaDeL: An Accurate Deep Learning-Based Model With Mutational Signatures for Predicting Metastasis Stage and Cancer Types.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Abdollahi Sina, Lin Peng-Chan, Chiang Jung-Hsien

Abstract excerpt

Mutational signatures help identify cancer-associated genes that are being involved in tumorigenesis pathways. Hence, these pathways guide precision medicine approaches to find appropriate drugs and treatments. The pattern of mutations varies in different cancer types. Some mutations dysregulate protein function so that their accumulation is responsible for cancer development and might be associated with...

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PMID: 34570707
DOI: 10.1109/TCBB.2021.3115504

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