Resolving mutational signatures in cancer development.

Abstract excerpt

In a recent Science study, an advanced mutational signature analysis was performed on an unprecedentedly large set of cancer whole-genome sequences across multiple organs. This work introduces a computational framework to identify common and rare mutational signatures and provides insights into their biological interpretation.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genome, Human
• Share to Mutation
• Share to Neoplasms