Article

On the discovered Cancer Driving Nucleotides (CDNs)–Distributions across genes, cancer types and patients

2024-06-02

Abstract excerpt

<h4>ABSTRACT</h4> A central goal of cancer genomics is to identify, in each patient, all the cancer driving mutations. Among them, point mutations are referred to as Cancer Driving Nucleotides (CDNs), which recur in cancers. The companion study shows that the probability of i recurrent hits in n patients would decrease exponentially with i ; hence, any mutation with i ≥ 3 hits in the TCGA database is a high-p...

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Literature Corpus work: 0568565c-bf81-5bbb-a849-aa18f09f252d
DOI: 10.1101/2024.05.29.596367

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