Article

Age-Associated Expression of DIMT1 (Dimethyladenosine Transferase) in Human Mesenchymal Stromal Cells: A Candidate for Multi-Gene Aging Signatures

2025-11-17

Abstract excerpt

<h4>Background</h4> DIMT1 is a highly conserved methyltransferase that functions as an N 6 ,N 6 -dimethyladenosine transferase responsible for modifying two adjacent adenosines in the 18S rRNA. This protein is also a crucial, yet catalytically independent, ribosome maturation factor essential for the biogenesis of the 40S small ribosomal subunit. Given the established roles of ribosome biogenesis and methylatio...

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Literature Corpus work: b7523491-525a-5c3f-a782-ebf3052a8594
DOI: 10.1101/2025.11.16.25340333

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