Article

Direct RNA sequencing reveals multi-layered regulation of the aging transcriptome

2025-10-15

Abstract excerpt

<title>Abstract</title> <p> <bold>BACKGROUND:</bold> Aging involves complex molecular alterations across tissues; however, a comprehensive understanding of epitranscriptomic dynamics remains elusive. <bold/> <bold>RESULTS:</bold> Here, leveraging high-quality dRNA-seq, we simultaneously constructed a multi-tissue (lung, skeletal muscle, heart, and hippocampus), cross-species (mouse and human) dynamics atlas...

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Literature Corpus work: 66869a20-9af0-5d33-81de-fd0cea6449b3
DOI: 10.21203/rs.3.rs-7521909/v1

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