Article

Estimating gene conversion rates from population data using multi-individual identity by descent

2025-02-27

Abstract excerpt

In humans, homologous gene conversions occur at a higher rate than crossovers, however gene conversion tracts are small and often unobservable. As a result, estimating gene conversion rates is more difficult than estimating crossover rates. We present a method for multi-individual identity-by-descent (IBD) inference that allows for mismatches due to genotype error and gene conversion. We use the inferred IBD to de...

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Literature Corpus work: 59ba7e99-3923-50f1-ac57-36ed9b8e7b0f
DOI: 10.1101/2025.02.22.639693

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