Article

A common polymorphism that protects from cardiovascular disease increases fibronectin processing and secretion

2021-03-09

Abstract excerpt

<h4>Background</h4> Fibronectin ( FN1 ) is an essential regulator of homodynamic processes and tissue remodeling which has been proposed to contribute to atherosclerosis. Moreover, recent large scale genome wide association studies have linked common genetic variants within the FN1 gene to coronary artery disease (CAD) risk. <h4>Methods</h4> Public databases were analyzed by two-Sample Mendelian Randomization...

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Literature Corpus work: b71ca514-6b05-56e5-bfc3-af31549efaef
DOI: 10.1101/2021.03.09.434522

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