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Article

Interindividual transcriptional regulation of the human biglycan gene involves three common molecular haplotypes.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2013

Schmitz Boris, Salomon Andrea, Rötrige Alois, Ritter Martin, Ringelstein E Bernd, Fischer Jens W, Paul Martin, Brand Eva, Brand Stefan-Martin

Abstract excerpt

OBJECTIVE: The extracellular matrix proteoglycan biglycan (BGN) is involved in cardiovascular disease pathophysiology, as it mediates the subendothelial retention of atherogenic apolipoprotein B-containing lipoproteins, affects adaptive remodeling after myocardial infarction, and exerts proinflammatory effects in macrophages. In a cardiovascular disease-related setting of vascular endothelial cells and human...

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Identifiers

PMID: 23393390
DOI: 10.1161/ATVBAHA.112.301073

Genes

BGN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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