Article

SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells

2022-03-30

Abstract excerpt

<title>Abstract</title> <p>Efforts to cure HIV have focused on reactivating latent proviruses to enable elimination by CD8+ cytotoxic T-cells. Clinical studies of latency reversing agents (LRA) in individuals treated with antiretroviral therapy (ART) have shown increases in HIV transcription, but without reductions in virologic measures, or evidence that HIV-specific CD8+ T-cells were productively engaged. Here,...

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Literature Corpus work: b6e745d9-73c8-522d-a16a-4a10de87007d
DOI: 10.21203/rs.3.rs-863118/v1

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