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Article

Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine

28 Jul 2021

Abstract excerpt

Abstract SARS-CoV-2 spike mRNA vaccines 1–3 mediate protection from severe disease as early as ten days after prime vaccination 3 , when neutralizing antibodies are hardly detectable 4–6 . Vaccine-induced CD8 + T cells may therefore be the main mediators of protection at this early stage 7,8 . The details of their induction, comparison to natural infection, and association with other arms of vaccine-induced...

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PMID: 34320609
DOI: 10.1038/s41586-021-03841-4

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