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Article

Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.

Journal of virology - 1 Oct 2015

Olesen Rikke, Vigano Selena, Rasmussen Thomas A, Søgaard Ole S, Ouyang Zhengyu, Buzon Maria, Bashirova Arman, Carrington Mary, Palmer Sarah, Brinkmann Christel R, Yu Xu G, Østergaard Lars, Tolstrup Martin, Lichterfeld Mathias

Abstract excerpt

UNLABELLED: The pharmaceutical reactivation of dormant HIV-1 proviruses by histone deacetylase inhibitors (HDACi) represents a possible strategy to reduce the reservoir of HIV-1-infected cells in individuals treated with suppressive combination antiretroviral therapy (cART). However, the effects...

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Identifiers

PMID: 26223643
DOI: 10.1128/JVI.01484-15
PMCID: PMC4580197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26223643-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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