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Insights into the HIV Latency and the Role of Cytokines

4 Sept 2019

Abstract excerpt

Human immunodeficiency virus-1 (HIV-1) has the ability to infect latently at the level of individual CD4+ cells. Latent HIV-1 proviruses are transcriptionally silent and immunologically inert, but are still capable of reactivating productive lytic infection following cellular activation. These latent viruses are the main obstacle in the eradication of HIV-1, because current HIV-1 treatment regimens are...

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PMID: 31487807
DOI: 10.3390/pathogens8030137

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