Article
Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary.
Nucleic acids research - 1 Jul 2012
Soshnev Alexey A, He Bing, Baxley Ryan M, Jiang Nan, Hart Craig M, Tan Kai, Geyer Pamela K
Abstract excerpt
The Drosophila Suppressor of Hairy-wing [Su(Hw)] protein is a globally expressed, multi-zinc finger (ZnF) DNA-binding protein. Su(Hw) forms a classic insulator when bound to the gypsy retrotransposon and is essential for female germline development. These functions are genetically separable, as exemplified by Su(Hw)(f) that carries a defective ZnF10, causing a loss of insulator but not germline function. Here, we...
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