Article
The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis.
Developmental biology - 15 Aug 2011
Baxley Ryan M, Soshnev Alexey A, Koryakov Dmitry E, Zhimulev Igor F, Geyer Pamela K
Abstract excerpt
The Drosophila Suppressor of Hairy wing [Su(Hw)] insulator protein has an essential role in the development of the female germline. Here we investigate the function of Su(Hw) in the ovary. We show that Su(Hw) is universally expressed in somatic cells, while germ cell expression is dynamic. Robust levels accumulate in post-mitotic germ cells, where Su(Hw) localization is limited to chromosomes within nurse cells,...
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