Article
Investigation of the properties of non-gypsy suppressor of hairy-wing-binding sites.
Genetics - 1 Jul 2008
Kuhn-Parnell Emily J, Helou Cecilia, Marion David J, Gilmore Brian L, Parnell Timothy J, Wold Marc S, Geyer Pamela K
Abstract excerpt
Insulators define interactions between transcriptional control elements in eukaryotic genomes. The gypsy insulator found in the gypsy retrovirus binds the zinc-finger Suppressor of Hairy-wing [Su(Hw)] protein that associates with hundreds of non-gypsy regions throughout the Drosophila genome. Models of insulator function predict that the gypsy insulator forms chromatin loop domains through interactions with...
Topics
- Alleles
- Animals
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Chromatin Immunoprecipitation
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Enhancer Elements, Genetic
- Eye
- Insulator Elements
- Molecular Sequence Data