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Drosophila <i>small ovary</i> gene ensures germline stem cell maintenance and differentiation by silencing transposons and organising heterochromatin

2018-08-02

Abstract excerpt

Self-renewal and differentiation of stem cells is one of the fundamental biological phenomena relying on proper chromatin organisation. In our study, we describe a novel chromatin regulator encoded by the Drosophila small ovary (sov) gene. We demonstrate that sov is required in both the germline stem cells (GSCs) and the surrounding somatic niche cells to ensure GSC survival and differentiation. Sov maintains n...

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Literature Corpus work
b1251897-6790-56e5-9a0f-b86309657d77
DOI
10.1101/383265
Open publication

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Drosophila <i>small ovary</i> gene ensures germline stem cell maintenance and differentiation by silencing transposons and organising heterochromatinDOI 10.1101/383265
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