Article

Isolation of genetically diverse influenza antibodies highlights the role of IG germline gene variation and informs the design of population-comprehensive vaccine strategies

2025-07-07

Abstract excerpt

The regular emergence of influenza strains with pandemic potential creates a strong incentive to develop vaccines that stimulate protective responses across all human populations. A critical consideration is how variation in the human immunoglobulin (IG) loci influences B cell recognition of viral epitopes and elicitation of neutralizing antibodies. Here, we applied personalized IG germline genotyping and high-thr...

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Literature Corpus work: b675fa92-69e4-50c1-9287-4f1c6e694f69
DOI: 10.1101/2025.07.04.663145

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