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Convergent antibody evolution and clonotype expansion following influenza virus vaccination

22 Feb 2021

Abstract excerpt

Recent advances in high-throughput single cell sequencing have opened up new avenues into the investigation of B cell receptor (BCR) repertoires. In this study, PBMCs were collected from 17 human participants vaccinated with the split-inactivated influenza virus vaccine during the 2016-2017 influenza season. A combination of Immune Repertoire Capture (IRCTM) technology and IgG sequencing was performed on ~7,800...

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Influenza Virus Research Studies
Monoclonal and Polyclonal Antibodies Research
T-cell and B-cell Immunology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33617543
DOI: 10.1371/journal.pone.0247253

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