Article

Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time

2021-03-31

Abstract excerpt

Ribosomal subunit biogenesis within mammalian cells initiates in the nucleolus with the assembly of a 90S precursor particle, which is subsequently split into the pre-40S and pre-60S subunits. During further processing steps, pre-ribosomal subunits are loaded with export receptors, which enables their passage through the pore complexes (NPCs) into the cytoplasm. Here export factors are released and both subunits c...

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Literature Corpus work: b66559fd-8bcd-515d-b4d9-68e0cf9de730
DOI: 10.1101/2021.03.30.437662

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