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Article

The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators.

Nature - 7 Jan 2016

Kaletsky Rachel, Lakhina Vanisha, Arey Rachel, Williams April, Landis Jessica, Ashraf Jasmine, Murphy Coleen T

Abstract excerpt

Insulin/insulin-like growth factor signalling (IIS) is a critical regulator of an organism's most important biological decisions from growth, development, and metabolism to reproduction and longevity. It primarily does so through the activity of the DAF-16 transcription factor (forkhead box O (FOXO) homologue), whose global targets were identified in Caenorhabditis elegans using whole-worm transcriptional...

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PMID: 26675724
DOI: 10.1038/nature16483
PMCID: PMC4708089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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