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Cognitive endophenotypes in racially- and ethnically-diverse middle-aged adult offspring aggregate with parental magnetic resonance imaging biomarkers of Alzheimer’s disease risk

2021-01-20

Abstract excerpt

A family history of Alzheimer’s disease (AD) increases risk for AD in an individual by 1.5-to 3-fold. Heritability of AD risk may be due in part to the aggregation of neurodegeneration and cerebrovascular changes with cognitive endophenotypes within families. The purpose of this study was to determine the extent to which cognitive functioning in middle-aged adults is associated with objectively-measured neurodegen...

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Literature Corpus work
b6532790-8da0-5356-b969-ecb74803c63e
DOI
10.1101/2021.01.15.21249832
Open publication

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Cognitive endophenotypes in racially- and ethnically-diverse middle-aged adult offspring aggregate with parental magnetic resonance imaging biomarkers of Alzheimer’s disease riskDOI 10.1101/2021.01.15.21249832
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