Article

Targeting the TLK1-Nek1-Mediated Activation of YAP1 Attenuates PD-L1 and Inflammation Set for Prostate Cancer Immunoevasion

2025-05-23

Abstract excerpt

For nearly a century, fundamental observations have demonstrated that prostate cancer (PCa) cells almost always require androgen receptor (AR) stimulation for sustained proliferation, leading to focused efforts to disrupt this pathway. Similarly, efforts have concentrated on understanding AR-driven processes in the context of elevated expression of its target genes, while significantly less emphasis has been place...

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Literature Corpus work: b636b3e3-e1cc-5857-bf45-4c04a0b87b45
DOI: 10.20944/preprints202505.1821.v1

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