Article

TLK1-MK5 axis drives prostate cancer cell motility and pathologic features of aggressiveness

2021-04-27

Abstract excerpt

<title>Abstract</title> <p>Background: Majority of prostate cancer (PCa) related fatalities occur due to metastasis of cancer cells to adjacent and distal organs. We identified the novel interaction between two kinases (TLK1-MK5) that in part may initiate a signaling cascade promoting PCa metastasis. In PCa, TLK1-MK5 signaling might be crucial as androgen deprivation therapy leads to increased expression of TLK1...

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Literature Corpus work: f8c092c2-6c6b-55bc-9488-8295592b5e31
DOI: 10.21203/rs.3.rs-434116/v1

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