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Article

Longitudinal Immune Profiling Reveals Unique Myeloid and T-cell Phenotypes Associated with Spontaneous Immunoediting in a Prostate Tumor Model.

Cancer immunology research - 1 May 2021

Ager Casey R, Obradovic Aleksandar Z, Arriaga Juan M, Chaimowitz Matthew G, Califano Andrea, Abate-Shen Cory, Drake Charles G

Abstract excerpt

The theory of cancer immunoediting, which describes the dynamic interactions between tumors and host immune cells that shape the character of each compartment, is foundational for understanding cancer immunotherapy. Few models exist that facilitate in-depth study of each of the three canonical phases of immunoediting: elimination, equilibrium, and escape. Here, we utilized NPK-C1, a transplantable prostate tumor...

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Source

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Identifiers

PMID: 33637604
DOI: 10.1158/2326-6066.CIR-20-0637
PMCID: PMC8102339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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