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Deep Post-GWAS Analysis Identifies Potential Risk Genes and Causal Variants for Alzheimer’s Disease, Providing New Insights Into Its Disease Mechanisms

2020-06-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>Alzheimer’s disease (AD) is a genetically complex, multifactorial neurodegenerative disease. It affects more than 45 million people worldwide and currently remains untreatable. Although genome-wide association studies (GWAS) have identified many AD-associated common variants, only about 25 genes are currently known to affect the risk of developing AD, despite its...

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Literature Corpus work: fb9a88c2-94f9-5402-aa7e-24dcc47639d7
DOI: 10.21203/rs.3.rs-31864/v1

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