Article

Under pressure: Keratin 9 regulates mechanosensitive YAP1 signaling in palmoplantar epidermis

2025-09-17

Abstract excerpt

<h4>ABSTRACT</h4> The palmoplantar epidermis, in adapting to the exceptional mechanical strain it bears during locomotion, is molecularly and histologically distinct from other skin body sites. The mechanisms specifying and maintaining its unique identity remain incompletely defined. Here, we identify the type 1 keratin 9 ( KRT9 /K9), a protein uniquely expressed in the palmoplantar epidermis, as a key modulator...

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Literature Corpus work: b607f7e2-abb0-56c5-b097-dd4ebd81cbb0
DOI: 10.1101/2025.09.15.676359

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