Article

Research on the mechanism by which USP18 promotes colorectal cancer progression through stabilizing KRT16 expression

2025-12-08

Abstract excerpt

<title>Abstract</title> <p>Background This study aims to investigate the effects of Ubiquitin-specific peptidase 18 (USP18) and Keratin16 (KRT16) on the progression of colorectal cancer and their possible mechanism of action. Methods The downstream target protein of USP18 was identified using Co-immunoprecipitation(Co-IP) and mass spectrometry. The clinical significance of KRT16 was validated via bioinformatics a...

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Literature Corpus work: b60430d3-ca41-5e9e-9cf0-3185dc4aa6ae
DOI: 10.21203/rs.3.rs-8191897/v1

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