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The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics

4 May 2022

Abstract excerpt

As a critical member of the ubiquitin-specific proteolytic enzyme family, ubiquitin-specific peptidase 20 (USP20) regulates the stability of proteins via multiple signaling pathways. In addition, USP20 upregulation is associated with various cellular biological processes, such as cell cycle progression, proliferation, migration, and invasion. Emerging studies have revealed the pivotal role of USP20 in the...

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PMID: 35508480
DOI: 10.1038/s41419-022-04853-2

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