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USP18 Is Associated with PD-L1 Antitumor Immunity and Improved Prognosis in Colorectal Cancer

21 Sept 2024

Abstract excerpt

BACKGROUND: Compared with conventional chemotherapy and targeted therapy, immunotherapy has improved the treatment outlook for a variety of solid tumors, including lung cancer, colorectal cancer (CRC), and melanoma. However, it is effective only in certain patients, necessitating the search for alternative strategies to targeted immunotherapy. The deubiquitinating enzyme USP18 is known to play an important role...

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Cancer Immunotherapy and Biomarkers
interferon and immune responses
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39334957
DOI: 10.3390/biom14091191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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