Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence

15 May 2025

Abstract excerpt

The aberrant expression of S100A11 has been identified in various malignancies but its functional roles and underlying mechanisms in colorectal cancer (CRC) have not been fully elucidated. Therefore, this study was designed to investigate the expression of S100A11 and its functional significance in CRC, indicating that S100A11 is significantly upregulated and correlates with poor survival outcomes in CRC....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clusterin in disease pathology
Share to Protease and Inhibitor Mechanisms
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40374593
DOI: 10.1038/s41419-025-07724-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescencePMID 40374593Read ↗

USP39 mediates p21‐dependent proliferation and neoplasia of colon cancer cells by regulating the p53/p21/CDC2/cyclin B1 axisSemantic proximity Read ↗

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer.Semantic proximity Read ↗

USP14 promotes colorectal cancer progression by targeting JNK for stabilizationSemantic proximity Read ↗

Ubiquitin Specific Protease 29 Functions as an Oncogene Promoting Tumorigenesis in Colorectal CarcinomaSemantic proximity Read ↗

USP14 promotes colorectal cancer progression by targeting JNK for stabilizationSemantic proximity Read ↗

USP21-EGFR signaling axis is functionally implicated in metastatic colorectal cancerSemantic proximity Read ↗

Loss of the proteasomal deubiquitinase USP14 induces growth defects and a senescence phenotype in colorectal cancer cells.Semantic proximity Read ↗

USP18 Is Associated with PD-L1 Antitumor Immunity and Improved Prognosis in Colorectal CancerSemantic proximity Read ↗

S100 protein family: Emerging role and mechanism in digestive tract cancer (Review)Semantic proximity Read ↗

Roles of USP9X in cellular functions and tumorigenesis (Review)Semantic proximity Read ↗

Identification of LncRNA NUSAP1 as a Novel Biomarker for Colorectal Cancer Progression and MetastasisSemantic proximity Read ↗

RSPO2 as Wnt signaling enabler: Important roles in cancer development and therapeutic opportunitiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.