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Article

Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in <i>Toxoplasma gondii</i>

2019-08-24

Abstract excerpt

Artemisinins are effective against a variety of parasites and provide the first line of treatment for malaria. Laboratory studies have identified several mechanisms for artemisinin resistance in Plasmodium falciparum , including mutations in Kelch13 that are associated with delayed clearance in some clinical isolates, although other mechanisms are likely involved. To explore other potential mechanisms of resistan...

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Literature Corpus work
b5c41558-c9f4-5e21-88b3-172c946451f5
DOI
10.1101/746065
Open publication

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Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in <i>Toxoplasma gondii</i>DOI 10.1101/746065
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