Article

Genetic mapping of lifespan and mitochondrial stress response in C. elegans

2025-07-31

Abstract excerpt

<title>Abstract</title> <p>The mitochondrial unfolded protein response (UPRmt) is one of the mito-nuclear regulatory circuits that restores mitochondrial function upon stress conditions, promoting metabolic health and longevity. However, the complex gene interactions that govern this pathway and its role in aging and healthspan remain to be fully elucidated. Here, we activated the UPRmt using doxycycline (Dox) in...

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Literature Corpus work: 9ca61455-4e1f-5591-a230-0b3585b423fc
DOI: 10.21203/rs.3.rs-7093535/v1

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