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Ether Lipid Biosynthesis Promotes Lifespan Extension and Enables Diverse Prolongevity Paradigms in <i>Caenorhabditis elegans</i>

2021-09-03

Abstract excerpt

Biguanides, including the world’s most commonly prescribed drug for type 2 diabetes, metformin, not only lower blood sugar, but also promote longevity in preclinical models. Epidemiologic studies in humans parallel these findings, indicating favorable effects of metformin on longevity and on reducing the incidence and morbidity associated with aging-related diseases. In spite of this promise, the full spectrum of...

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Literature Corpus work
dda9a9d4-4c5b-5a8c-9a84-7a22f9a4404b
DOI
10.1101/2021.09.02.457410
Open publication

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