Article

A genetically encoded tool to increase cellular NADH/NAD <sup>+</sup> ratio in living cells

2022-09-20

Abstract excerpt

<h4>ABSTRACT</h4> Impaired reduction/oxidation (redox) metabolism is a key contributor to the etiology of many diseases, including primary mitochondrial disorders, cancer, neurodegeneration, and aging. However, mechanistic studies of redox imbalance remain challenging due to limited strategies which can perturb cellular redox metabolism and model pathology in various cellular, tissue, or organismal backgrounds wi...

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Literature Corpus work: b55104d8-dd64-5737-8da1-9af47b483577
DOI: 10.1101/2022.09.20.508785

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