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Article

Tolerance to NADH/NAD <sup>+</sup> imbalance anticipates aging and anti-aging interventions

2019-07-31

Abstract excerpt

<h4>Summary</h4> Redox couples coordinate cellular function, but the consequences of their imbalances are unclear. This is somewhat associated with the limitations of their experimental quantification. Here we circumvent these difficulties by presenting a new approach that characterizes fitness-based tolerance profiles to redox couple imbalances using an in silico representation of metabolism. Focusing on the NA...

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Identifiers and source

Literature Corpus work
13745381-0975-5f1f-b561-2c04b46399b6
DOI
10.1101/719401
Open publication

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Tolerance to NADH/NAD <sup>+</sup> imbalance anticipates aging and anti-aging interventionsDOI 10.1101/719401
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