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Article

Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing.

Stem cells (Dayton, Ohio) - 1 Jan 2019

Adkar Shaunak S, Wu Chia-Lung, Willard Vincent P, Dicks Amanda, Ettyreddy Adarsh, Steward Nancy, Bhutani Nidhi, Gersbach Charles A, Guilak Farshid

Abstract excerpt

The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and drug screening. In many cases, however, these differentiation approaches are poorly controlled and generate heterogeneous cell populations. Here, we demonstrate...

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Identifiers

PMID: 30378731
DOI: 10.1002/stem.2931
PMCID: PMC6312762

Genes

COL2A1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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