Article

Prospective Isolation of Chondroprogenitors from Human iPSCs Based on Cell Surface Markers Identified using a CRISPR-Cas9-Generated Reporter

2019-06-19

Abstract excerpt

<h4>SUMMARY</h4> Articular cartilage shows little or no capacity for intrinsic repair, generating a critical need for regenerative therapies for joint injuries and diseases such as osteoarthritis. Human induced pluripotent stem cells (hiPSCs) offer a promising cell source for cartilage tissue engineering and in vitro human disease modeling; however, heterogeneity and off-target differentiation remain a challenge...

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Literature Corpus work: 0df514eb-96da-557e-96cf-33cc627f909b
DOI: 10.1101/675983

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