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Human Induced Pluripotent Stem Cells Differentiated into Chondrogenic Lineage <i>Via</i> Generation of Mesenchymal Progenitor Cells

21 Jul 2012

Abstract excerpt

Human induced pluripotent stem cells (hiPSCs) exhibit pluripotency, proliferation capability, and gene expression similar to those of human embryonic stem cells (hESCs). hESCs readily form cartilaginous tissues in teratomas in vivo; despite extensive effort, however, to date no efficient method for inducing mature chondrocytes in vitro has been established. hiPSCs can also differentiate into cartilage in vivo by...

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PMID: 22817676
DOI: 10.1089/scd.2012.0127

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