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Increased Infectivity of Human Cytomegalovirus Strain TB40/E Conferred by Variants of the Envelope Glycoprotein UL128 and the Regulatory Protein IE2

2025-04-16

Abstract excerpt

Human cytomegalovirus (HCMV) infects various cell types in its human host, and this broad tropism plays a vital role in viral transmission, dissemination, and pathogenesis. HCMV strains differ in their ability to infect and replicate in different cell types, but the genetic determinants of cell tropism have only begun to be understood. A widely used HCMV strain, TB40/E, contains a mixture of genetically distinct v...

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Literature Corpus work
b5395d5d-451b-5e5c-8ccd-5e112bd47ec7
DOI
10.1101/2025.04.09.647953
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Increased Infectivity of Human Cytomegalovirus Strain TB40/E Conferred by Variants of the Envelope Glycoprotein UL128 and the Regulatory Protein IE2DOI 10.1101/2025.04.09.647953
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