Single nuclei chromatin accessibility and transcriptomic map of breast tissues of women of diverse genetic ancestry

Abstract excerpt

<title>Abstract</title> <p>Single nuclei analysis is allowing robust classification of cell types in an organ that helps to establish relationships between cell-type specific gene expression and chromatin accessibility status of gene regulatory regions. Using breast tissues of 92 healthy donors of various genetic ancestry, we have developed a comprehensive chromatin accessibility and gene expression atlas of huma...

Topics

Open a Topic to create a Post that cites this publication.

• Chromatin
• Cluster Analysis
• Fetus
• Genome, Human
• Genome-Wide Association Study
• Organ Specificity
• Regulatory Sequences, Nucleic Acid
• Single-Cell Analysis

Identifiers and source

Literature Corpus work

b506f66b-c905-5993-b6c9-6766ff0fec3a

DOI

10.21203/rs.3.rs-3411051/v1