Article

Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves

2020-02-15

Abstract excerpt

<h4>Background</h4> Bioprosthetic heart valves (BHV) are widely used to treat heart valve disease but are fundamentally limited by structural valve degeneration (SVD). Non-calcific mechanisms of SVD entirely account for approximately 30% of SVD cases and contribute to calcific SVD but remain understudied. Glycation mechanisms have not been previously associated with SVD, despite being established as degenerative...

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Literature Corpus work: b501f2d0-5283-5207-80e0-b0c4158d8f41
DOI: 10.1101/2020.02.14.948075

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