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Article

Age related extracellular matrix and interstitial cell phenotype in pulmonary valves

7 Dec 2020

Abstract excerpt

Heart valve disease is a common manifestation of cardiovascular disease and is a significant cause of cardiovascular morbidity and mortality worldwide. The pulmonary valve (PV) is of primary concern because of its involvement in common congenital heart defects, and the PV is usually the site for prosthetic replacement following a Ross operation. Although effects of age on valve matrix components and mechanical...

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PMID: 33288823
DOI: 10.1038/s41598-020-78507-8

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