Article

Surface Anticoagulation of Mechanical Heart Valves using Electrically Induced Biomimetic Glycocalyx: an In-vitro study to assess Hemocompatibility and Optimal Voltage

2025-11-04

Abstract excerpt

<h4>Background</h4> Mechanical heart valves (MHVs) remain the most durable option for valve replacement, but they are highly thrombogenic and therefore necessitate life-long anticoagulation. We designed a novel MHV assembly based on “Surface Anticoagulation by Electrically induced Biomimetic Glycocalyx” (SAEBG) that imposes a weak negative potential across the valve’s blood-contacting surfaces using an implantabl...

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Literature Corpus work: 5409cebc-428f-56a6-98d0-cf6bff531477
DOI: 10.1101/2025.11.02.25339348

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Surface Anticoagulation of Mechanical Heart Valves using Electrically Induced Biomimetic Glycocalyx: an In-vitro study to assess Hemocompatibility and Optimal VoltageDOI 10.1101/2025.11.02.25339348Read

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